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Pharmacology General 23f357af

Biguanides acts by following except -

A
|Insulin release from pancreas
B
| Glycolysis
C
| Gluconeogenesis
D
| Insulin binding to its receptors
High-Yield Explanation
Ans. is 'a' i.e., | insulin release from pancreash Biguanides acts by : o Suppress hepatic gluconeogenesis and glucose output from liver major action. o Enhance insulin mediated glucose disposal in muscle and fat (Increased peripheral utilization of glucose) by enhancing GLUT-I transpo from intracellular site to plasma membrane. o Retad intestinal absorption of glucose. o Promote peripheral glucose utilization by enhancing anaerobic glycolysis.

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