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Pediatrics General 23de5102

All of the following syndromes are associated with AML except -

A
Down's syndrome
B
Klinefelter's syndrome
C
Patau syndrome
D
Turner's syndrome
High-Yield Explanation
Ans. is 'D' i.e., Turner's syndrome Risk Factors of AML: Genetic disorders :Down syndrome ,Klinefelter syndrome ,Patau syndrome ,Ataxia telangiectasia, Shwachman syndrome ,Kostman syndrome, Neurofibromatosis ,Fanconi anemia ,Li-Fraumeni syndrome Physical and chemical exposures: Benzene Drugs such as pipobroman, Pesticides ,Cigarette smoking, Embalming fluids. Herbicides. Radiation exposure :Nontherapeutic, therapeutic radiation Chemotherapy :Alkylating agents ,Topoisomerase-II inhibitors, Anthracyclines, Taxanes

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