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Medicine Polycystic Kidneys 23c477ee

Which of the following is FALSE regarding Autosomal dominant polycystic kidney disease (ADPKD)

A

Berry aneurysm is the most common CNS manifestation

B

Increased risk of subarachnoid from a ruptured intracranial aneurysm

C

Polyductin gene is involved in ADPKD

D

Saccular aneurysms may be detected in up to 10% of asymptomatic patients

High-Yield Explanation

* In ADPKD, mutations in the PKD1 gene on chromosome 16 (ADPKD-1) account for 85% of cases * Mutations in the PKD2 gene on chromosome 4 (ADPKD-2) account for the remainder

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