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Medicine General 23beb36b

Good pasture's syndrome is charachterized by:

A
Anti-GBM antibodies
B
Crescenteric glomerulonephritis
C
Diffuse alveolar haemorrhage
D
All of the above
High-Yield Explanation
Answer is D (All of the above): Harrison's syndrome is typically associated with anti-GBM antibodies, crescenteric glomerulonephritis (RPGN) and diffuse alveolar haemorrhage `Good pasture's syndrome is charachterized by the combination of Diffuse Alveolar Haemorrhage (DAH) and glomerulonephritis (Crescents; RPGN) associated with anti-gomerular basement membrane (GBM) antibodies in serum or evident on immunofluorescent staining of renal or lung tissue. The sine-qua-non of Good pasture's syndrome is the demonstration of linear deposition of Ig -G - immunoglobulin (IgG) along the alveolar capillary or GBM.' - Kelly Essentials of Internal Medicine

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