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Medicine Endocrinology 23bd9dc0

Somatostatin is produced by:

A
A cell
B
B cell
C
D cell
D
F cell
High-Yield Explanation
Ans: c (D cell) Ref: Robbins, 7th ed, p. 1189Alpha cell-GlucagonsBeta cell-insulinD cell-somatostatinF cell-pancreatic polypeptideSomatostatinomaVIPomaMost common site - Head of pancreasOther names - Vemer Morrison syndrome. Water diarrhea syndrome, WDHA syndromeClinical features - Diabetes mellitus - Gall bladder diseasePancreatic cholera- DiarrhoeaMost common site - Tail of pancreas- SteatorrhoeaClinical features - Watery diarrhea - Hypokalaemia- Hypochlorhydria- Metabolic acidosis- Hypercalcaemia- hyperglycaemiaInsulinomaIt is an endocrine tumour of beta cells. Only 5-15% are malignant.Most common site of Insulinoma -distributed equally all over pancreasWhipple's triad1) Symptoms consistent with hypoglycaemia2) A low plasma glucose concentration3) Relief of symptoms after the plasma glucose level is raisedThese features are typically seen in insulinoma.

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