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Anatomy Other topics and Adverse effects 237f8403

Which of these drugs DO NOT decrease angiotensin Il activity

A
Enalapril
B
Valsaan
C
Nesiritide
D
Omapatrilat
High-Yield Explanation
(Ref: Katzung 10/e p205, 286) ACE inhibitors and AT1, antagonists decrease angiotensin Il activity. Omapatrilat is a vasopeptidase inhibitor that acts by inhibiting two enzymes, ACE and NEP. As it inhibits ACE, it may also decrease angitotensin II activity. Nesiritide is a recombinant BNP and has no effect on angiotensin II activity.

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