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Physiology General 23620186

During acclimatization to high altitude all of the following take place except

A
Increase in minute ventilation
B
Increase in the sensitivity of central chemoreceptors
C
Increase in the sensitivity of carotid body to hypoxia
D
Shift in the oxygen dissociation curve to the left
High-Yield Explanation
At high altitude there can be acute changes and changes due to acclimatization. Acute mountain sickness Dyspnoea, dizziness, tiredness, tachycardia, palpitation, nausea, vomiting etc. At higher altitudes- pulmonary edema and cerebral edema may occur. Acclimatization changes Hyperventilation leading to respiratory alkalosis Increased 2,3DPG- Hb-O2 dissociation curve shifts to right. Increased erythropoietin leading to absolute polycythemia Increased renal excretion of bicarbonate Increased tissue vascularity Increased oxidative metabolism Increased diffusion capacity of lung Increased myoglobin

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