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Gynaecology & Obstetrics General 232992ec

During population-based screening programs, a 40 years old lady found to have cervical intraepithelial neoplasia. Which of the following is the treatment modality for this patient?

A
Cryotherapy
B
LEEP
C
Cold knife conization
D
All of the above
High-Yield Explanation
The 5 most common techniques for the treatment of CIN include 2 ablative techniques--cryotherapy and laser ablation--and 3 excisional procedures--cold knife conization, laser cone excision, and LEEP. That these techniques are of equal efficacy, averaging 80-90% success rates in the treatment of CIN. Cure depends on the size of the lesion, endocervical gland involvement, margin status of any excisional specimen, and endocervical curettage results. Ref: Holschneider C.H. (2013). Chapter 48. Premalignant & Malignant Disorders of the Uterine Cervix. In A.H. DeCherney, L. Nathan, N. Laufer, A.S. Roman (Eds), CURRENT Diagnosis & Treatment: Obstetrics & Gynecology, 11e.

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