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Gynaecology & Obstetrics Abortion 225db713

Commonest cause of first trimester abortion is:

A
Monosomy
B
Trisomy
C
Triploidy
D
Aneuploidy
High-Yield Explanation
Ans. is d, i.e. AneuploidyRef. Williams 24/e, p 351The M/C cause of early miscarriages is aneuploidy (i.e. chromosomal anomaly).Amongst the aneuploid abortions--autosomal trisomy is the most frequently identified chromosomal anomaly.Trisomies have been identified in abortuses for all except chromosomal number 1 and those with 16, 13, 18, 21 and 22 are most common.The single most specific chromosomal abnormality in abortions is Monosomy X (45X).As a have discussed Best answer for M/C cause of 1st trimester abortion--Aneuploidy > Trisomy > Monosomy X > Trisomy 16.

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