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Unknown General 21f4d1d7

True about phlyctenular conjunctivitis are all, except-

A
Endogenous allergy
B
Caused by staphylococcus
C
Type II hypersensitivity
D
Usually unilateral
High-Yield Explanation
Ans. is 'c' Type II hypersensitivity Phlyctenular keratoconjunctivitis o Phlyctenular conjunctivitis is an allergic response of the conjunctival and corneal epithelium to some endogenous allergens and characterized by formation of the phlyctens. Phlyctens are grey, yellow or pinkish white nodules slightly raised above the surface, are seen on the bulbar conjunctiva, generally near the limbus. Peak age group is 3-15 years with slight female preponderance. Etiology o It is believed to be a delayed hypersensitivity (Type IV cell mediated) response to endogenous microbial proteins. Causative allergens are : - i) Staphylococcus proteins (most common); ii) Tuberculous proteins iii) Proteins of Moraxella axenfeld bacillus and certain parasites. Symptoms o Disease is usually unilateral (in contrast to vernal keratoconjunctivitis which is bilateral). There is mild irritation, discomfort and lacrimation. Itching is not prominent as seen in vernal keratoconjunctivitis, o Phlyctens are pinkish white nodules at limbus. Phlyctens are surrounded by hvperamia (congestion) and this congestion of vessels is limited to the area around phlyctens. Phlyctens ulcerate at apex, o Corneal involvement may result in miliary ulcer, ring ulcer, fascicular ulcer or sacrofulous ulcer. There may be diffuse infiltrative phlyctenular keratitis. Treatment o Topical steroids are the DOC.

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