Drug contraindicated in bilateral renal aery stenosis

Refer kDT 6/e p 484 Renal aery stenosis is thenarrowing of one of the renal aeries, most often caused by atherosclerosis or fibromuscular dysplasia. This narrowing of therenal aery can impede blood flow to the target kidney, resulting in renovascular hypeension - a secondary type of high blood pressure. Angiotensin-conveing enzyme inhibitors (ACEIs) arecontraindicated in patients withbilateral renal aery stenosis due to risk of azotemia resulting from preferential efferent aeriolar vasodilation in the renal glomerulus due to inhibition of angiotensin II.