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Pharmacology Pharmacodynamics 2137c01b

Administration of which of the following drug requires therapeutic drug monitoring?

A
Lithium
B
Haloperidol
C
Diazepam
D
Acetazolamide
High-Yield Explanation
Therapeutic drug monitoring is adjustment of dose of the drug according to its plasma concentration. It is required for A Aminoglycosides (e.g. gentamicin) Drug Digitalis Possessing Phenytoin (anti-epileptics) Low Lithium Therapeutic Tricyclic antidepressants Index Immunomodulators (e.g. cyclosporine) Range of 0.8-1.2 mEq/L is ored for treatment of acute manic or hypomanic patients. 0.6-1.0 mEq/l is considered adequate and safer for long term prophylaxis.

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