A 30-year-old male had severely itchy papulo–vesicular lesions on extremities, knees, elbows and buttocks for one year. Immunofluorescence staining of the lesions showed IgA deposition at dermo-epidermal junction. The most probable diagnosis is –
High-Yield Explanation
Itchy papulovesicular lesions on extensor surfaces and deposition of IgA at DEJ suggests the diagnosis of dermatitis herpatiformis, which is associated with Coeliac disease