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Pathology Neoplasia 20f915e1

Translocation associated with follicular thyroid carcinoma is?

A
PAX8- PPARrl
B
RET - PTC
C
ALK-NMP1
D
JAK-TEL
High-Yield Explanation
Ans is 'a' i.e. PAX8- PPARrl Various genes involved in thyroid carcinomas arePapillary* Tyrosine kinase receptors RET or NTRK1* RAS mutation* BRAF oncogeneFollicular* RAS oncogene (NRAS, HRAS and KRAS* PAX8- PPARrl translocationMedullary* RET proto-oncogene

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