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Medicine General 20c9f7ee

Which of the following is the best marker for drug induced lupus?

A
Anti histone antibodies
B
Anti DS DNA
C
ANA
D
Anti Smith Ab
High-Yield Explanation
Drug induced lupus is associated with anti histone antibodies which are positive in 95% of cases. Ref: Harrison's Principles of Internal Medicine, 17th Edition, Page 2076; 16th/ 1961, 1967; Pathologic Basis of Disease, Robbins, 7th Edition, Page 229 & 235; Drug-Induced Diseases: Prevention, Detection, and Management, James E. Tisdale, 2nd Edition, Section 2, Page 108

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