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Microbiology General 20a7afd5

E6, E7 genes of which virus are implicated in oncogenesis ?

A
EBV
B
CMV
C
HTLV- 1
D
HPV
High-Yield Explanation
Ans. is 'd' i.e., HPV HPV selectively infects the epithelium of skin and mucous membrane and may immoalize the keratinocytes leading either asymptomatic infection, or was or neoplasia. Products of E-genes (E6, E7) are related to immoalization or malignant transformation of keratinocytes by interfering with p53 and Rb genes, respectively.

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