Anticipation is seen in -

Ans. is 'c' i.e., Trinucleotide-repeat expansion Anticipation o Anticipation is a phenomenon where by the symptoms of a genetic disorders become apparent at an earlier age as it is passed to next generation. In most cases, an increased severity of symptoms is also noted. In triplet nucleotide repeat mutation, the DNA fragment is unstable and tends to expand fuher during cell division. So, in succesive generations the expanded repeat increases and the manifestations of disease may worsen or to be observed at an earlier age; this phenomenon is referred to as anticipation.