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Medicine General 20404172

Low Renin Hypeension is seen in all of the following, Except:

A
Essential hypeension
B
Conn's syndrome
C
Renovascular hypeension
D
Liddle's syndrome
High-Yield Explanation
Answer is C (Renovascular Hypeension): Renovascular Hypeension is associated with High Renin levels (High Renin Hypeension) Addle Syndrome is associated with Low Renin and Low Aldosterone levels Liddle's syndrome is an autosomal dominant condition caused by mutations in the genes that encode the p and 7 subunits of the mineralocoicoid-dependent epithelial sodium channel. This results in continuous (constitutive) activation of the channel, even in the absence of mineralocoicoid. Clinically, the condition is characterised by early-onset hypeension, with hypokalemia and low levels of rennin and aldosterone. The condition responds to treatment with the potassium-sparing diuretic Amiloride (or triamterene).

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