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General Medicine General 20127af5

A 50-year-old lady presented with a 3-month history of pain in the lower third of the right thigh. There was no local swelling; tenderness was present on deep pressure. Plain X-rays showed an ill-defined intra medullary lesion with blotchy calcification at the lower end of the right femoral diaphysis, possibly enchondroma or chondrosarcoma. Sections showed a cartilaginous tumor. Which of the following histological features (if seen) would be most helpful to differentiate the two tumours?

A
Focal necrosis and lobulation
B
Tumor permeation between bone trabeculae at periphery
C
Extensive myxoid change
D
High cellularity

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