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Pharmacology General 1e9fcec4

Which of the following is a Dihydropteroate synthase (DHPS) inhibitor?

A
Pyrimethamine
B
Trimethoprim
C
Methotrexate
D
Dapsone
High-Yield Explanation
Dapsone, PAS, Sulphonamide > inhibit DHPS enzyme Pyrimethamine, Methotrexate, Trimethoprim - acts by inhibiting DHFR (Dihydrofolate reductase) enzyme.

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