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Pharmacology General 1e48dbd9

Drug of choice for drug induced parkinsonism?

A
Levodopa
B
Anticholinergic
C
Selegiline
D
Carbidopa
High-Yield Explanation
Ans is 'b' i.e., Anticholinergic "Central anticholinergics are the only drugs effective in drug induced parkinsonism." o They act by reducing unbalanced cholinergic activity in the striatum of parkinsonism patients. Generally, tremor is benifited more than rigidity; hypokinesia is affected the least (Levodopa resolves hypokinesia and rigidity first and later tremor). Trihexyphenidyl (benzhexol) is the most commonly used anticholinergic in parkinsonism.

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