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Medicine General 1e2aade3

All of the following are seen in oliguric phase of Acute Tubular necrosis, Except:

A
Hypernatremia
B
Hypermagnesemia
C
Hyper uricemia
D
Hyper phosphatemia
High-Yield Explanation
Answer is A (Aminoglycoside toxicity): Non-Oliguric Renal Failure is typically associated with Aminoglycoside toxicity. 'Aminoglycoside nephrotoxicity typically is associated with non-oliguric renal failure' - Management of Acute Kidney Problems 'Non-Oliguric renal failure is a common expression of aminoglycoside nephrotoxity and may reflect a direct inhibitory effect on solute transpo along the thick ascending loop of Hence or possibly tubulointerstitial cell injury. - Diseases of Kidney and Urinary Tract 81h/1035 'Non-Oliguric Acute Kidney Injury accompanies 10-30% of courses of aminoglvcosides even when plasm levels are in therapeutic range'- Harrison 18th/2298 'The Acute Kidney Injury of Aminoglycoside toxicity is characteristically non-oliguric and reversible with a low moality' - 'Renal and Electrolyte Disorders' by Sh -icy (Lippincott Williams) 2010/357-358 Non-Oliguric renal failure may also be associated with contrast induced nephropathy, however it is most typical /characteristic of Aminoglycoside toxity.

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