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Gynaecology & Obstetrics General 1e1a2f09

Concerning fibroids:

A
Use of GnRH analogues cause permanent reduction in size
B
Pregnancy following myomectomy is about 80%
C
Recurrence rate following myomectomy is about 30%
D
Growth factors (IGF-1, EGF) stimulates myoma to grow
High-Yield Explanation
Option a: Incorrect as regrowth of myoma occurs after 3 months of GnRH therapy Option b: Is also incorrect as pregnancy rate following myomectomy is 50–60% and not 30%. Option c: Recurrence rate is 1%, 10% and not 30% hence it is also incorrect. Option d: “Epidermal growth factor (EGF), insulin like growth factor (IGF 1), transforming growth factor (TGF), stimulate the growth of the leiomyoma either directly on via estrogen” Dutta Gynae 6th/ed p 272. Hence option d is correct.

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