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Microbiology Systemic Bacteriology (Gram Positive Bacilli, Gram Negative Bacilli) 1de12cd4

In which of the following sites is Salmonella typhi most likely to be found during the carrier state?

A
Blood
B
Gallbladder
C
Kidney
D
Liver
High-Yield Explanation
Salmonella typhi is the most likely to be found in gall bladder during the carrier state. Carriage: Up to 5% of patients become carriers. - The carrier state is more common in women than in men and in the older people (over 40 years) than in young people. - Carriers usually harbour the organisms in the gallbladder or biliary tract. - Type of Carriers:- Convalescent - shed bacilli for 3 weeks-3 months after clinical cure. Temporary - shed bacilli for 3 months to 1 year after clinical cure. Chronic - shed bacilli for more than 1 year. - Carriers can be diagnosed by stool/ urine culture or sewer swab culture. - Treatment of carriers: Ampicillin or Amoxicillin + probenecid for 6 months.

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