Microbiology
General Microbiology Pa 1 (History, Microscopy, Stains and Structure and Physiology of Bacteria)
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Which of the following statement is false regarding bacterial cell wall?
High-Yield Explanation
Difference between Gram positive cell wall and gram negative cell wall Structure Primary Functions Chemical Constituents Gram- Positive cell wall Peptidoglycan osmotic stability, structural integrity, cell shape; permeable to antibiotics Thick meshwork of peptide cross-linked polysaccharide chains Teichoic and lipoteichoic acids Adhesion to host cells, weak endotoxin activity, antigenic Polymers of substituted ribitok or glycerol phosphate Proteins Adhesion to host cells, antiphagocytic, antigenic Examples: streptococcal M and R proteins Gram-Negative cell wall Peptidoglycan See above Thinner version of that found in gram-positive bacteria Periplasmic space Transpo of nutrients, degradation of macro molecules Between cytoplasmic and outer membranes - carrier proteins and hydrolytic enzymes Outer membrane Structural suppo, uptake of metabolites, permeability barrier, protection, antigenic Phospholipid bilayer, porins, transpo and other proteins, lipopolysaccharide Lipopolysaccharide Endotoxin activity (Lipid A), anticomplement activity (O antigen) Three pas: Lipid A, core polysaccharide, O antigen Porin channel Allow small and hydrophilic molecules to pass outer membrane Porin proteins