In Potters syndrome - primary pathology is:

b. Renal agenesis(Ref: Nelson 20/e 2513)Components of oligohydramnios complex (Potter syndrome), including low-set ears, micrognathia, flattened nose, limb positioning defects, intrauterine growth restriction & death may result from pulmonary hypoplasia.Bilateral renal agenesis is incompatible with extrauterine life & produces the Potter syndrome.