Drug contraindicated in sever hyperiglyceri- demia is -

Severe hyperiglyceridemia (SHTG) is well known to be associated with severe diseases such as acute pancreatitis and cardiovascular disease. According to the literature, SHTG is the most common cause for acute pancreatitis after gallstones and alcohol Both of these studies included patients with normal triglyceride levels or mild hyperiglyceridemia. Niacin is contraindicated in patients with active peptic ulcer disease, but can be used safely in patients with glucose intolerance and can be considered in diabetic patients with moderate to good glycemic control. Ref Davidson 23rd edtion pg 719