Bortezomib drug used in -

Ans. is 'a' i.e., Multiple myeloma Uses of bortezomib:o The prime indication of bortezomib is multiple myeloma, both for first line combined therapy as well as for replapsed disease.o It is also used for refractory mantle cell lymphoma.Note: The most prominent adverse effect of bortezomibis peripheral neuropathy. Others are diarrhea, fatigue, bone marrow depression especially thrombocytopenia.