Pharmacology Mycobacterial Diseases (TB, Leprosy and MAC) 1d004cf3

Which of the following is mechanism of action of dapsone?

Inhibit the cell wall synthesis

Inhibit the sterol of cell wall

Inhibit the protein synthesis

Compete with PABA in folic acid synthesis

High-Yield Explanation

Dapsone is analogue of PABA Competively inhibits dihyropteroate synthase - decreases folic acid synthesis. It can cause mild hemolysis, anemia and psychosis. Uses: Leprosy Malaria Prophylaxis of pneumocystitis Dermatitis herpetiformis

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Which of the following is mechanism of action of dapsone?

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