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Unknown General 1c8153c9

Antihypertensive not used in the management of PIH is:

A
Hydralazine
B
Propranolol
C
Labetolol
D
Alpha methyldopa
High-Yield Explanation
Ref. KDT. Page. 145 Anti-hypertensives to be avoided during pregnancy Diuretics: Tend to reduce blood volume— accentuate uteroplacental perfusion deficit (of toxaemia)—increase risk of foetal wastage, placental infarcts, miscarriage, stillbirth. ACE inhibitors, AT antagonists: Risk of foetal damage, growth retardation. Nonselective b blockers: Propranolol has been implicated to cause low birth weight, decreased placental size, neonatal bradycardia and hypoglycaemia. Sod. nitroprusside: Contraindicated in eclampsia. Antihypertensives found safer during pregnancy Hydralazine
Methyldopa (a positive Coombs’ test occurs, but has no adverse implication). Dihydropyridine CCBs: discontinue before labour as they weaken uterine contractions. Cardioselective b blockers and those with ISA, e.g. atenolol, metoprolol, pindolol, acebutolol: may be used if no other choice.
 Prazosin and clonidine—provided that postural hypotension can be avoided.

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