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Medicine General 1bfe123f

All are true about familial male limited precocious pubey, EXCEPT:

A
It is also called Testotoxicosis
B
Autosomal dominant condition
C
Testosterone and LH levels are elevated
D
Flutamide can be used for treatment
High-Yield Explanation
Familial male limited precocious pubey is also called testotoxicosis. FACTS : It is an autosomal dominant disorder It presents as premature androgenization of boys Testosterone is elevated, LH is suppressed in the condition Treatment options : 1. Ketoconazole - Inhibits testosterone synthesis. 2. Flutamide - Used as an androgen receptor antagonist. 3. Anastrazole - Is a useful aromatase inhibitor. Ref: Harrison, Edition - 18, Page - 3015

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