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Biochemistry General 1bae5f07

Vitamin C is the co-enzyme for the following hydroxylases EXCEPT

A
Peptidyl glycine hydroxylase
B
Dopamine betahydroxylase
C
Prolyl/ lysyl hydroxylase
D
Aspartate betahydroxylase
High-Yield Explanation
-Vitamin C plays the role of a coenzyme in hydroxylation of proline and lysine while protocollagen is converted to collagen  (i.e.  post-translational modification). The hydroxylation reaction is catalysed by lysyl hydroxylase  (for  lysine)  and prolyl  hydroxylase (for  proline). -Hydroxylation of  glycine  is  carried  out  by peptidylglycine  hydroxylase which  requires vitamin C. -Ascorbic acid  is required  for  the  oxidation  of  p-hydroxy phenylpyruvate (enzyme hydroxylase) to homogentisic acid in tyrosine metabolism.

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