Pharmacology Targeted Anticancer Drugs and Immunosuppressants 1b9fb3e2 Which of the following drugs inhibits de novo synthesis of purines? A Cyclosporine B Tacrolimus C Mycophenolate D Infliximab High-Yield Explanation By inhibiting the enzyme IMP (Inosine 5' Monophosphate) dehydrogenase, mycophenolate inhibits the de novo synthesis of purines.