A 68 yr old woman with a repeated bouts of pneumonia and H/O heavy smoking presents with a 2-week history of fever and productive cough. A chest X-ray reveals a right lower lobe infiltrate and trans-bronchial biopsy confirms pneumonia and there occurs preneoplastic changes within the bronchial mucosa. Which of the following best characterizes the morphology of this bronchial mucosal lesion?
A
Cellular maturation shows abnormal pattern
B
Increased numbers of otherwise normal cells
C
Invasiveness
D
presence of poorly diiferentiated keratin producing cells