In hepatic metabolism, phase II reactions are:

- Metabolic Reactions    Phase 1 (non-synthetic) - Functional group is attached to the drug molecule. §  Oxidation §  Reduction §  Hydrolysis §  Cyclization §  Decyclization    Phase 2 (synthetic) - Conjugate is attached to the drug molecule. §  Glucuronidation §  Acetylation §  Methylation §  Sulfation §  Glycine conjugation