Surgery General 1a72ab3e The most impoant determinant of prognosis in Wilm's tumor is - A Stage of disease B Loss of heterozygosity of chromosome Ip C Histology D Age less than 1 yr at presentation High-Yield Explanation Ans. is 'c' i.e. Histology "The histology of Wilm's tumor was identified as the most impoant determinant of prognosis." - Devita's Cancer