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Pathology Liver 1a6cd1a2

Regarding Cause of fatty liver, true statement about pathogenesis is:

A
Decreased beta oxidation of fat
B
Decreased triglycerides
C
Decreased fatty acid mobilization
D
Increased catabolism
High-Yield Explanation
Ref: Chapter L Ceil injury: page: 34: Robbins and Cot ran Pathologic Basis of Disease: 8th editionExplanation:There are various mechanism of triglycerides accumulation in the liver; defect in any steps of fat metabolism can cause this: like defect in uptake, catabolism, secretion can result in lipid accumulation.The free fatty acids are esterified in the liver to form triglycerides.Then the triglycerides will be either converted to cholesterol/ phospholipids or oxidized to ketone bodies.Excess accumulation of triglycerides within the liver may result from excessive entry or defective metabolism and export of lipids.

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