The treatment of Hodgkin's disease of stomach is -

• Primary gastric Hodgkin’s disease is extremely rare (<1% of all gastric lymphomas) • Stomach is the MC site of primary extranodal lymphoma in adults Etiology: • Association of classic Hodgkin’s disease with EBV • LMP1 (Latent Membrane Protein 1) an essential EBV protein, commonly expressed and associated with the pathogenesis of Hodgkin’s disease Diagnosis: • Endoscopy: Non-specific gastritis or peptic ulcers with mass lesions • A full panel of immunohistochemical markers is essential to make an accurate diagnosis of gastric Hodgkin’s disease. Treatment: • Hodgkin’s disease of the stomach has been treated by surgery while post operative chemotherapy has been employed for systemic disease. Prognosis: • Prognosis is poor with 45–60% of patients dying within the first year of diagnosis