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Pathology Cellular Pathology 1a582e2e

In apoptosis, cytochrome C acts through:

A
Apaf 1
B
Bcl-2
C
FADD
D
TNF
High-Yield Explanation
Ans. (a) Apaf 1(Ref Robbins 9th/pg 54-55; 8th/pg 29)Leakage of cytochrome c, other proteins form the inner mitochondrial membrane to cytosol|Cytochrome C binds to APAF-1Q|Activation of caspase-9-critical initiator caspase of the mitochondrial pathway

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