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Physiology General 1a55af44

Vibration sensation (low frequency) is mediated by:

A
Merkel’s disc
B
Ruffini’s end organ
C
Pacinian corpuscle
D
Meissner’s corpuscle
High-Yield Explanation
Merkel’s disc is the only touch receptor located in epidermis.  Touch and pressure are sensed by four types of mechanoreceptors. Meissner corpuscles are dendrites encapsulated in connective tissue and respond to changes in texture and slow vibrations. Merkel cells are expanded dendritic endings, and they respond to sustained pressure and touch. Ruffini corpuscles are enlarged dendritic endings with elongated capsules, and they respond to sustained pressure. Pacinian corpuscles consist of unmyelinated dendritic endings of a sensory nerve fiber, 2 μm in diameter, encapsulated by concentric lamellae of connective tissue that give the organ the appearance of a cocktail onion. These receptors respond to deep pressure and fast vibration. The sensory nerves from these mechanoreceptors are large myelinated Aα and Aβ fibers whose conduction velocities range from ~70–120 to ~40–75 m/s, respectively.

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