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Unknown General 1a4e7b02

Antidote in Atropine poisoning is -

A
Flumazenil
B
Physostigmine
C
Naloxone
D
NaHCO3
High-Yield Explanation
Ans. is 'b' i.e., Physostigmine o Atropine blocks cholinergic receptors. o So, for atropine overdose, we require a drug that increases cholinergic action, o Physostigmine increases the concentration of Ach. o Physostigmine counteracts central (because it crosses BBB) as well as peripheral symptoms of atropine toxicity (other anticholinesterases like neostigmine and pyridostigmine counteract only peripheral symptoms as they cannot cross BBB) - Physostigmine is the DOC.

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