Full 2L QBank
Pharmacology Miscellaneous (Pharmacology) 1a1b847c

Contraindication for the triptans is which of the following?

A
Ischemic heart disease
B
Epilepsy
C
Hepatic failure
D
All of the above
High-Yield Explanation
Ans. is 'd' i.e., All of the above Triptans* These are 5-HT1D/1B receptor agonists.* Sumatriptan is the 1st triptan to be developed. It is the drug of choice for aborting an acute attack of migraine.* Other triptans in clinical use are Almotriptan, eletriptan,frovatriptan, rizatriptan, eletriptan, naratriptan, and zolmitriptan.* All triptans can cause coronary vasospasm and are contraindiated in IHD. Other contraindications are hypertension, epilepsy, hepatic or renal impairment and during pregnancy.* The most important adverse effects are feeling of chest pressure, tightness and pain which may he accompanied by arrhythmia and MI and appear to be due to coronary vasospasm.

Related Pharmacology MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now