True about wound healing

• Epidermal appendages do not regenerate • There remains a connective tissue scar in place of the mechanically efficient meshwork of collagen in the unwounded dermis. • Very superficial wounds: Little scar formation. • In marked contrast with wound healing in adults, fetal cutaneous wounds heal without scar formation, up to mid-gestation age in some animals. These wounds show little inflammation and practically no fibrosis. Cutaneous wound healing is divided into three phases • Inflammation (early and late) • Granulation tissue formation and re-epithelialization • Wound contraction, ECM deposition and remodeling