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Pathology Miscellaneous 19eab568

Which of the following zone of the liver lobule is more prone to ischemia?

A
Peripoal
B
Midzonal parenchyma
C
Centrilobular zone
D
All zones are affected equally
High-Yield Explanation
Centrilobular zone (zone 3) is zone with poor oxygenation , therefore is more prone to ischemia * Liver is divided histologically into lobules. * The center of the lobule is the central vein. * At the periphery of the lobule are poal triads. * Based on the oxygen supply , the liver can be divided into three zones. Zone 1 : Peripoal zone - encircles the poal tracts where the oxygenated blood from hepatic aeries enters. Zone 2 : Midzonal parencyma - is located in between. Zone 3 : Centrilobular Zone - is located around central veins, where oxygenation is poor.

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