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Pharmacology Autonomic nervous system 19cd9862

Which of the following antiglaucoma medications are not safe in infants

A
Timolol
B
brimonidine
C
Latanoprost
D
Dorzolamide
High-Yield Explanation
Apraclonidine and brimonidine can cross blood brain barrier and can cause CNS depression and Apnea in neonates. therefore these are contraindicated in children less than 2 years of age Refer Goodman and Gilman 12e p1788,kdt 6/e 168

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