Wire loop lesions are often characteristic for the following class of lupus nephritis:

Answer is C (Diffuse Proliferative Glomerutonephritis) Wire loop lesions are most charachteristic of diffuse proliferative glomerulonephritis (Class IV WHO) but may also be seen in focal proliferative glomerulonephritis (Class III WHO). Most characteristic of: Lupus Nephritis Class IV (Diffuse Lupus Nephritis) Also seen in: Lupus Nephritis Class III (Focal) > Lupus Nephritis Class V (Membranous)