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Pathology Haematology 19987bb1

C-MYC translocation is seen in which of the following tumors?

A
Burkitt lymphoma
B
Neuroblastoma
C
Malignant melanoma
D
Breast cancer
High-Yield Explanation
All forms of Burkitt lymphoma are highly associated with translocation of the MYC gene on chromosome 8 that lead to increased MYC protein levels.The translocation paner for MYC is usually the IgH locus but may also be the Ig . Ref :Robbins pathologic basis of disease ; south east asia edition ;pg:597

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