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Pharmacology Anaesthesia 196973c3

Which of the following is used as a preanaesthetic medication?

A
Propanthelene
B
Glycopyrrolate
C
Ipratropium bromide
D
Hyoscine
High-Yield Explanation
Ans. is 'b > d' i.e., Glycopyrrolate > Hyoscine Drugs used in premedication1.Sedative - antianxiety-Diazepam/Lorazepam/Midazolam.-Lorazepam is used most commonly-Midazolam is used for day care surgery2.Opioids-Morphine/Pethidine3.Anticholinergics-Atropine/ Hyoscine/ Glycopyrrolate.4.Neuroleptics-Haloperidol/chlorapromazine/triflupromazine5.H2 blocker or proton pump inhibitor-Ranitidine/Famotidine, omeprazole/Pantoprazole.6.Antiemitics-Metoclopramide/ Domperidone/ Ondansetron/ Hyoscine/ Ondansetron* To control secretion, anticholinergics (Glycopyrrolate, atropine or scopolamine) are used. Gycopyrrolate is a preferred anticholinergic over atropine and scopolamine (hyoscine) because it does not crosses blood brain barrier and devoid of central side effects.Note: Atropine is a natural alkaloid, used in OPC poisoning and has profound central CNS effects.

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