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Anatomy Other topics and Adverse effects 190c7613

Shanti has been diagnosed to have brain tumor. You would prefer to give her betamethasone/dexamethasonc over hydrocoisonc as steroids to decrease her cerebral edema because:

A
They do not cause Na+ and water retention
B
They are more potent
C
They can be administered intravenously
D
They inhibit brain tumours
High-Yield Explanation
(Ref: KDT 6/e p285) Triamcinolone, betamethasone, dexamethasone and paramethasone are selective glucocoicoids (have zero mineralocoicoid action). These are preferred for cerebral edema because they lack salt and water retaining potential (mineralocoicoid action).

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