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Gynaecology & Obstetrics General 189909e3

A case of Gestational Trophoblastic Neoplasia belongs to high risk group if disease develops after:

A
Hydatidiform mole
B
Full term pregnancy
C
Spontaneous abortion
D
Ectopic pregnancy
High-Yield Explanation
High risk gestational trophoblastic disease. FIGO in 2000 devised a staging system for categorisation of gestational trophoblastic neoplasia into good prognostic (low risk) and bad prognostic (high risk) disease. Good prognosis (Low risk) Short duration (< 4 months) Serum β-hCG < 40,000 mIU/ml Metastasis limited to lung and vagina No significant prior chemotherapy  No preceding term pregnancy  Bad prognosis (Low risk) Long duration (> 4 months) Serum 6-hCG > 40,000 mIU/ml Metastasis to brain or liver Unsuccessful prior chemotherapy Gestational trophoblastic neoplasia following term pregnancy. Also if we have a look at the WHO prognostic scoring system: GTN following a term pregnancy comes under high risk. Remember: High risk GIN occurs after term pregnancy . GTN occurs most commonly after H mole.

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